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Abnormal Haemoglobins Overview
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Haemoglobinopathies are a group of hereditary diseases that result as a consequence of defect(s) in the genes responsible for the synthesis of haemoglobin. Depending on the molecular defect, haemoglobinopathies may be classified as either thalassaemias or structural hemoglobin variants.

Consequently a robust haemoglobinopathy screening method needs to be able to:

  • Accurately quantify HbF and HbA2 for the screening of ß-thalassemia
  • Reliably separate and identify common and clinically significant structural hemoglobin variants.

Our available haemoglobinopathy instrumentation is detailed below, which ultilises the principles of Ion Exchange Chromatography to give the very best separation possible.

You can also read more about variant haemoglobins here.

Ultra 2™ Variant


The Ultra2™ Variant incorporates a 4 minute Quick Scan program and a 10.5 minute High Resolution program for unattended screening and confirmation of haemoglobin variants.

 

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